Journal of AdvancedMedical and Dental Sciences Research

In recent years, the most important role in the regulation of immunopathological mechanisms, in particular allergic reactions, has been assigned to cytokines. The aim of the study is to assess the characteristics of the immunological nature in children suffering from atopic dermatitis. The majority of patients have a burdened heredity for allergies and an increased level of IgE. Apparently, the severity of AD is determined not by the level of Ig E in the blood serum, but by the influence of triggers on the development of allergic inflammation. The results obtained will allow one to better navigate the functional disorders of the immune system of children with AD and can be used for adequate therapy. Key words: atopic dermatitis, children, allergy, cytokines, immunity, immunopathogenesis, interleukins