Journal of AdvancedMedical and Dental Sciences Research

Aim: The aim of this study is to ascertain C-reactive protein levels in patients with periodontitis and to correlate it with clinical parameters. Methods: The case control study consisted of 100 test group patients diagnosed with periodontitis and 100 control group patients with no periodontitis using clinical parameters. A detailed case history was recorded. Clinical parameters like plaque index, gingival index and probing pocket depth and biochemical parameters like C - reactive protein were assessed. The values obtained were compared by statistical analysis using student’s T- test and Pearsons’ correlation. Results: Plaque index, gingival index, probing pocket depth and C-reactive protein levels were significantly higher in test group as compared to control group (P ≤ 0.001). Significant positive correlation was observed between the clinical parameters and biochemical parameters. Conclusion: Periodontal status was poorer in patients of test group as compared to control group. The c-reactive protein levels were notably higher in patients with test group as compared to control group. A significantly positive correlation was seen between test and control group. Keywords: Periodontal disease, C - reactive protein, periodontitis, inflammation, acute phase proteins.