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Volume 4 Issue 2 (March - April, 2016)

Original Articles

Clinico- pathological evaluation of specimens of Gall Bladder
Paritosh Mohan, Sherry Kapur, Amit Varshney

Background: Cholelithiasis produces diverse histopathological changes in mucosa ranging from acute inflammation to dysplasia and carcinoma. The present study was conducted to assess clinical and histopathology of specimens of gall bladder. Materials & Methods: 68 gall bladder specimens were fixed in 10% formalin. Gross examination findings along with characteristic of stones, relevant clinical history were noted. Results: Out of 68 specimens, 48 were from males and 20 were from females. Common clinical features were pain abdomen seen in 45, fever in 20, jaundice in 29 and vomiting in 34. Histopathological findings were acute acalculus cholecystitis in 13, chronic calculus cholecystitis in 24, xanthogranulomatous cholecystitis in 8, follicular cholecystitis in 5, mucocele in 6, cholesterolosis in 4, gangrenous cholecystitis in 5 and carcinoma gall bladder in 3 patients. The difference was significant (P< 0.05). Conclusion: Most of the lesions found to be chronic calculus cholecystitis. Key words: Chronic calculus cholecystitis, Gallbladder, Histopathology.

 
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