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Volume 9 Issue 1 (January, 2021)

Original Articles

Assessment of hepatic dysfunction in Dengue fever
Sagar Shah, Amit Palange, Anusha Allu, Sudarshan Lamture

Background: Dengue virus infection has varied clinical implications, ranging from patients presenting with no symptoms to landing up in critical conditions like Dengue hemorrhagic fever and Dengue shock syndrome. The present study was conducted to assess hepatic dysfunction in Dengue fever. Materials & Methods: 100 symptomatic Dengue serology positive patients of both sexes were investigated for complete blood counts, serum dengue IgM or IgG antibodies. Liver function tests, Ultrasound abdomen and chest X-Ray were done. Results: 97% of patients had fever, myalgia was present in 85%, headache in 80%, retro orbital pain in 77%, pain in abdomen in 32%, bleeding tendencies were present in 14%, altered sensorium in 7% and arthralgia in 2% of the patients overall. 36 cases had hepatomegaly present, 6 cases had epigastric tenderness and 2 cases had tenderness in right hypochondrium present. Hepatomegaly was the most common per abdomen finding. Conclusion: Serum AST and ALT levels are significantly elevated in all forms of dengue virus infection- DF, DHF, DSS and also it correlates with severity of dengue virus infection. We also found that serum AST were significantly raised in comparison to serum ALT levels in all the 3 forms of dengue virus infection Key words: Chest X-Ray, Dengue, Ultrasound abdomen.

 
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