Journal of AdvancedMedical and Dental Sciences Research

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units. It is a pleomorphic disorder with multifactorial pathogenesis. The many expressions of acne rarely present a diagnostic challenge, but correct classification of acne is crucial in choosing the appropriate therapies. Although previous research has provided a better understanding of the pathogenic factors, there is still a great deal to be learned. Obstruction of follicles causes follicular distention, which is often accompanied by the proliferation of the bacteria Propionibacterium acnes and the activation of an inflammatory response. Although the diagnosis of acne is usually straightforward, some conditions are occasionally confused with acne, including periorificial dermatitis, keratosis pilaris, angiofibromas, bacterial folliculitis, and demodex folliculitis. In addition to physical discomfort, acne is associated with considerable psychological distress, limitation of activities, and increased risk of depression and suicide.
Key Words: Acne Vulgaris, Pathophysiology, Treatment