Journal of AdvancedMedical and Dental Sciences Research

The areca nut, popularly known as “betel nut” is almost symbolic of the culture of some Oriental nations and is one of the oldest known masticatories among Asians. Areca nut is consumed in various forms such as betel quid (areca nut + slaked lime + betel leaf) with or without tobacco, pan masala (Powdered areca nut with additives, flavoring agents and tobacco) and raw areca nut (seeval flakes and kotta pakku granules). There has been an increase in the use of areca nut, particularly pan masala in younger age groups in India, leading to increased incidence of OSMF. Many patients with OSMF have other habits concurrently, which may also play a role in the initiation and the progress of this pre-malignant condition.
Key Words: Areca Nut, Oral submucous fibrosis, Betel Quid, HLA