Journal of AdvancedMedical and Dental Sciences Research

Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share a phenotype of hyperglycemia. The prevalence of dyslipidemia in type 2 diabetes is double with respect to the general population. Dyslipidemia is an important risk factor for cardiovascular disease (CVD) and plays a major role in the progress of atherosclerosis. In present study, the levels of biochemical parameters like serum uric acid and serum lipid profile were evaluated and correlated for the risk of macrovascular disease in type 2 diabetes mellitus. Materials and method: The study population was selected among patients attending the Medicine O.P.D, Muzaffarnagar Medical College, Muzaffarnagar. Controls for the study population were patients of age (30-60 years) with type 2 Diabetes Mellitus. The student t-test, chi-square test and Pearson’s correlation test were used. Results: The correlation showed that uric acid showed a significantly positive correlation with Total cholesterol, triglyceride level and LDL. Whereas, there was a significantly negative correlation of uric acid with HDL. Conclusion: Diabetes mellitus is strongly associated with hyperuricemia. The present study shows a strong association between SUA and lipid profile among diabetic adults in our study. Early prevention of hyperuricemia and dyslipidemia can reduce the incidence of associated cardiovascular disease. The glycaemic control has got a strong impact on the serum lipid level and dyslipidemia is frequently encountered among individuals with poor glycaemic control. Keywords: Diabetes Mellitus, Dyslipidemia, serum lipid level, Total cholesterol.