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Volume 7 Issue 3 (March, 2019)

Original Articles

Assessment of salivary copper levels in oral submucous fibrosis patients
Abhishek Choudhary, Hemant Sharma, Harsh Choudhary

Background: Oral submucous fibrosis (OSMF) is a well-recognised-potentially malignant condition of the oral cavity associated with areca nut chewing. Hence; the present study was undertaken for assessing the salivary copper levels in OSMF patients. Materials & methods: A total of 30 OSMF patients and 30 age and gender matched healthy controls were included in the present study. Complete demographic details of all the patients were obtained. Salivary samples were obtained from all the patients in vials and were sent to laboratory where salivary copper levels were analysed using auto-analyser. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: Mean salivary copper levels among the patients of the OSMF group and the control group was 0.0421 µg/ml and 0.0178 µg/ml respectively. On analysing statistically, it was found that mean salivary copper levels of the patients of the OSMF group were significantly higher in comparison to the patients of the control group. Conclusion: Copper plays a definitive role in the etio-pathogenesis of OSMF. Key words: Copper, Oral submucous fibrosis

 
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