Journal of AdvancedMedical and Dental Sciences Research

Background: Spinal block has the incidence of being exclusively safe technique till the physiological values are within limits beyond that, complications of the technique starts seeming. The aim of the present study was to assess complications and hemodynaamic stability associated with the use of dexmedetomidine with bupivacaine vs fentanyl with bupivacaine in spinal anaesthesia undergoing orthopedic lower limb surgeries. Materials and methods: Patients with the spinal surgery, infection on back, neurological problems or hepatic disorders were not included in the study. A total of 30 patients were enrolled in the study belonging to ASA grade I or ASA grade II group. With random sampling method patients were divided two groups- Group I received dexmedetomidine 5 µg with hyperbaric bupivacaine 17.5 mg in 3.5 mL and Group II received fentanyl 25 µg with hyperbaric bupivacaine 17.5 mg in 3.5 mL. Patients were regarded to have bradycardia if heart rate was less than 40 while hypotension was regarded when mean arterial pressure was less than 50 in our study. Adverse reactions were noted during surgery. All the data thus obtained was arranged in a tabulated form and analyzed using SPSS software. Probability value of less than 0.05 was regarded as significant. Results: In dexmedetomidine group, it was 585+/-121.87 and in Fentanyl group, it was 288.63+/-171.62. On applying student t test, there was a significant difference between the two groups. There was 1 subject in dexmedetomidine Group and 2 in Fentanyl Group with hypotension. There was no significant difference between the groups. Conclusion: The duration of analgesia was significantly higher with the addition of dexmedetomidine compared to fentanyl but the incidence of side effects was comparable between the two groups. Key words: Adrenoreceptor, bupivacaine, dexmedetomidine, hemodynamic.