Categories

Volume 7 Issue 11 (November, 2019)

Original Articles

A Retrospective Study of 6 Years to evaluate Clinico - Histopathological Correlation in Leprosy
Nitu Sharma, Raja Chaterjee

Background: Clinical diagnosis of early leprosy lesions poses difficulties. Present study was conducted to evaluate the correlation between clinical and histopathological diagnosis of Leprosy. Materials and method: Two hundred patients reported between 2010 and 2015, in whom leprosy was clinically diagnosed or suspected and histo-pathological examinations were carried upon were involved in the study. Results: Results showed that most of the cases belonged to Borderline Borderline (BB) leprosy {50 cases, 25.0%} and minimum {11 cases, 5.5%} were of Histioid (HL) subtype of leprosy. On histopathological study Borderline borderline (BB) subtype of leprosy was found dominant 26 (13.0%) among all subtypes of leprosy followed by Tuberculoid (TT) subtype 26 cases (13.0%). Correlation between clinical and Histopathological diagnosis P=0.032 according to pearson’s rank correlation. Highest (94.511%) clinicohistopathological agreement was found in Intermediate Leprosy (IL) and highest (42.85%) disagreement was found in Borderline Line leprosy (BL). Conclusion: Since, there is some degree of overlap in different types of leprosy, the correlation can be made more accurate by combining clinical and histopathological features. Skin biopsy may be studied in all cases of leprosy for better diagnosis. Key words: Leprosy, Histopathology, Skin biopsy.

 
Html View | Download PDF | Current Issue