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Volume 7 Issue 10 (October, 2019)

Original Articles

Comparative evaluation of efficacy and safety of topical Luliconazole and Amorolifine in the treatment of tinea corporis
Anna Javed, Vijay Khajuria, Vishal R. Tandon, Rajesh Sharma

Background: Fungal infection of skin is a significant public health problem. They are caused by three genera of dermatophytes; Trichophyton, Microsporum and Epidermophyton. The present study was a comparative evaluation of efficacy and safety of topical luliconazole and amorolifine in the treatment of tinea corporis. Materials & Methods: The present study was conducted on 70 patients. Group I patients received topical application of Luliconazole (1%) and Group II patients received topical application of Amorolfine (0.25%). Clinical examination was done on all patients for determining the number of lesion, type, presence of inflammatory margins and extent of involvement. Size of lesion, margin of the lesion, erythema, scaling and itching was noted. Mycological examination was also done with KOH mount. Baseline score (Day 0) was assessed before applying topical medication. Post treatment scores on all parameters were taken on day 7, 14, 21, and 28. Results: Out of 70 patients, males were 40 and females were 30. There was significant difference in size of lesion in all days (P< 0.05). There was significant difference in size of lesion in all days (P< 0.05). Conclusion: Authors found that both 1% Luliconazole and 0.25% Amorolifine were effective in management of tinea corporis. Key words: Dermatophytes, Trichophyton, Microsporum

 
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