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Volume 7 Issue 9 (September, 2019)

Original Articles

Bacteriological Profile and Antibiotic Sensitivity of Cellulitis in a Tertiary Care Hospital
Kirti Savyasacchi Goyal, Amandeep Kaur, Mani Garg, Mohit Madhukar

Introduction: Cellulitis is an acute inflammatory condition of the skin characterised by localised pain, erythema, swelling and heat. It may be caused by indegenous flora colonizing the skin and associated appendages (e.gStaphylococcus aureus and Streptococcus pyogenes) or by a wide variety of exogenous bacteria. Cellulitis usually follows a breach in the skin, such as a cut, fissure, laceration, or puncture wound. In some cases, there is no obvious source of entry and the break may be due to microscopic changes in the skin or invasive qualities of certain bacteria. The aim is to study the profile of microorganisms causing cellulitis and the antibiotic profile of pathogens. Material and methods: The present cohort study was conducted 50 patients admitted in surgical wards of MMIMSR with diagnosis of cellulitis admitted in the Department of General Surgery, MMIMSR, Mullana, distt. (Ambala). Antimicrobial sensitivity of all the isolates will be performed and correlated with epidemiological factor i.e age, sex, history of trauma, concomitant diseases like diabetes. Specimens will be collected either by sterile swab or needle aspiration. Results: The study included a total of fifty patients, with age ranging from 21 years to 70 years. Out of the total 50 swabs obtained for microscopic examination by gram staining, majority 35(70%) were showing gram positive cocci while only 15 (30%) were showing gram negative bacilli. Among the gram positive organisms, isolates were Staphylococcus aureus (65.7%) and streptococci (34.3%). In gram negative isolates, most common organism was found to be pseudomonas (25%). Among the gram positive isolates, all (100%) were sensitive to vancomycin and imepenam while among the gram negative isolates, antibiotic sensitivity testing showed maximum sensitivity to imipenem (100%), followed by piperacillin-tazobactam (93.4%). Conclusion: To conclude, it was observed that there were more gram positive organisms causing cellulitis. Most common organisms responsible was staphylococcus aureus (65.7%) followed by streptococci(34.3%).All the gram positive and gram negative organisms were sensitive to vancomycin and imepenam respectively. However changing pattern of bacterial infection and drug resistance must be considered during treatment of petients. Key words: Cellulitis, Gram positive, Gram negative, culture, sensitivity.

 
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