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Volume 7 Issue 7 (July, 2019)
Original Articles
Evaluation of Alkaline Phosphatase in Gingival Crevicular Fluid among Chronic Periodontitis Patients with Smoking Habit | |
K. Hameed Fathima, V.S.Harish | |
Background: This study was done to evaluate the level of alkaline phosphatase as potential biochemical gingival crevicular fluid marker among chronic periodontitis patients with smoking habit. Materials and methods: A total of 80 subjects were selected for the study. The study population was further divided into 4 group (Group 1 – clinically healthy periodontium, Group – 2 gingivitis, Group – 3 periodontitis and Group - 4 smokers with periodontitis) .Based on clinical assessment of probing depth , bleeding on probing and radiographic evaluation of alveolar bone loss , gingival crevicular fluid samples were taken to assess the level of enzymes . Results: Obtained results shows statistically significant increase in the level of alkaline phosphatase activity in gingival crevicular fluid from periodontitis patients with smoking habit . There was positive correlation between the activity of examined gingival crevicular fluid enzymes and values of the plaque index , gingival index and periodontal disease index. Conclusion: Based on these results, it can be assume that alkaline phosphatase activity in gingival crevicular fluid may be used as potent biochemical markers for periodontal destruction. Received: 13 March, 2019 Revised: 22 April 2019 Accepted: 25 April 2019 |
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