Journal of AdvancedMedical and Dental Sciences Research

Platelet-rich fibrin (L-PRF) is an autogenous matrix derived from the concentration of the patient’s blood platelets. A simplified chair side procedure results in the production of a fibrin membrane that is capable of stimulating the release of many important growth factors involved during wound healing processes that take place after surgery. Platelet-rich fibrin can play an important role in oral and maxillofacial surgery, implant dentistry, periodontal regeneration and post-extraction site preservation. The fibrin is a reservoir of platelets that will slowly release growth factors and cytokines, which are the key factors for regeneration of the bone and maturation of the soft tissue. Platelet-rich fibrin (PRF) is an autologous platelet concentrate prepared from the patient’s own blood at the dentist’s office just before the oral/dental procedure. This review highlights the brief about PRF, advantages, disadvantages and it’s applications in dentistry.
Key words: Blood clot, Platelet-rich fibrin, Regenerative endodontic treatment, Fibrin, Platelet concentrate.

Received: 8 February, 2019                               Revised: 27 February, 2019                     Accepted: 28 February, 2019
Corresponding Author: Dr. Rahul Srivastava, Reader, Department of Oral Medicine & Radiology, Rama Dental College, Hospital & Research Centre Kanpur (U.P.), India

This article may be cited as: Srivastava R,  Mukherjee S, Saxena S, Saha S. A Novel Healing Platelet Rich Fibrin (PRF) matrix and its Role in Dentistry. J Adv Med Dent Scie Res 2019;7(4): 19-22.