Journal of AdvancedMedical and Dental Sciences Research

A Caries Vaccination is a programmed approach to pre immunized and protect caries prone people mainly children by using proteins present on oral flora bacterial surfaces mainly Streptococcus mutans (antigens) themselves for inducing human body to produce antibodies against these antigens naturally. For decades, a dental vaccine has been the topic of mucosal immunology and infectious disease research. Apparently, the main focus of the dental research is on the development of safe and efficacious oral anti-mutant vaccines. Vaccination against caries is based on the idea that the same principles that apply to mucosal immunity are applicable to protection against caries. Keywords: Caries vaccine, dental caries, streptococcus mutans, immunity.