Volume 5 Issue 3 (March, 2017)

Original Articles

Arun Puri, Parul Garg, Ishwer Tayal, Navtej Singh, Rupam

Background: Liver is vulnerable to a wide variety of metabolic, toxic, microbial and circulatory insults. Liver involvement due to various etiologic agents can either be primary in nature or can be secondary to cardiac de-compensation, alcoholism or extrahepatic infections. For assessing the cause of the death and for planning the medical strategies, autopsy study is useful. Hence, we planned the present study to evaluate various patterns of hepatic diseases which are morphologically reflected at the time of autopsy.Materials & methods: The present study included assessment of 200 autopsy viscera cases examined during 2011 to 2016. Gross examination of liver and other organs was done in the present autopsy study. After fixing all the specimens with 10 percent formalin solution, paraffin embedded wax blocks were made. All the sections were stained with H and E. All the demographic details, age, sex and other clinical findings of the cases were recorded and analyzed.Results: Out of total of 200 cases, majority of the pathologies were due to circulatory disorders. Hepatitis and cirrhosis were responsible for 37 and 11 cases respectively. Only three cases were of neoplastic pathology. Steatosis was responsible for 14 percent of the cases. Out of 200 cases, 107 were males and 93 were females. Circulatory disorders were the most common liver pathology among males. Among cases with age group of 40 to 50 years, the most common pathology detected was circulatory disorders.Conclusion: Various circulatory disorders, cirrhosis, hepatitis and steatosis are among the most commonly encountered liver pathologies.
Key words: Autopsy Viscera, Liver, Pathology, Cirrhosis, Fatty change.

Corresponding Author: Dr. Arun Puri, Professor, Deptt of Pathology, GMC Amritsar, Punjab, India.

This article may be cited as:Puri A, Garg P, Tayal I, Singh N, Rupam. Analysis of various hepatic pathologies in autopsy cases: A Retrospective Study. J Adv Med Dent Scie Res 2017;5(3):105-109.

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