Journal of AdvancedMedical and Dental Sciences Research

Background: Dengue fever is a disease spread by the Aedes aegypti mosquito and is caused by one of four dengue viruses. This mosquito is a tropical and subtropical species widely distributed around the world. Dengue is characterized by leucopenia followed by thrombocytopenia. In general, dengue is a self-limiting acute febrile illness followed by a phase of critical defervescence, in which patients may improve or progress to a severe form. Severe illness is characterized by hemodynamic disturbances, increased vascular permeability, hypovolemia, hypotension, and shock. Materials and methods:  Data were collected from patients attending outpatient and inpatient services in a hospital in North India. Total 58 patients of both sexes with age 35±10 years admitted with fever and found to have thrombocytopenia are included in the study. Data were collected after obtaining consent in due format. Data are collected by using interview, physical examination, sputum examination, and laboratory findings. Result:  Out of 58 cases with severe thrombocytopenia, complications were present in 36 cases.19  patients had haemorrhagic dengue fever, 5 suffer from severe dehydration, 3 from DHF with bleeding manifestation, 3 from dengue shock syndrome, 2 from fever induced seizures, 4 from neurological complications. Conclusion: It one of the most common vector-borne diseases worldwide.There was no predilection for any age group or gender for thrombocytopenia or bleeding among the dengue patients.
Key words: Dengue, thrombocytopenia, Fever, Platelet count, Dengue Shock syndrome (DSS).

Corresponding author: Dr. Rajesh Kumar Khare, Associate Professor, Department of Medicine, Integral Institution of Medical Sciences & Research Lucknow, U.P.  (India)

This article may be cited as: Khare RK,  Raj P. Dengue fever with thrombocytopenia and it’s complications: A hospital based study.  J Adv Med Dent Scie Res 2017;5(3):72-75.