Journal of AdvancedMedical and Dental Sciences Research

Background: Blood donation is considered to be the best donation in India. A single drop can save one’s life. Hence efforts have been taken to provide as much as blood required to the needy as possible. The present study was conducted to find the prevalence of Transfusion Transmitted Infectious markers and their trends among the blood donors. Materials & Methods: The study was conducted in from year 2009 to year 2012 to determine the prevalence of TTIs among blood donors. This study consisted of 5010 voluntary blood donor. 4520 (90.3%) was males and 490 (9.7%) was females. For detection of HIV infection, 3rd generation Microlisa was used to detect the HIV Antigen and antibody in donor serum. For detection of Hepatitis B infection, 4th generation Hepalisa was used for detection of Hepatitis B Surface Antigen and for detection of Hepatitis C virus infection,  4th generation HCV Microlisa was used for detection of HCV Antibody in serum or plasma of donor. For detection of syphilis infection, Sero-Max RPR (slide agglutination method) was used for VDRL screening. For screening of malarial infection, Pan Malaria Rapid and Qualisa ELISA (Tulip Group) were used. Results: Out of 5010 voluntary blood donor, 4520 (90.3%) was males and 490 (9.7%) was females. The difference was significant (P-0.01). The mean age of males was 38 years and in females 35 years. The difference was non significant (P-0.1). Overall prevalence of HIV (0.1%), HBsAg (1.3%), HCV (0.5), syphilis (0.07) and malaria (1%). The difference was significant (P<0.05). Yearly prevalence of HIV, HBsAg, syphilis, malaria and HCV. The prevalence of HIV reported in year 2009 was 0.1%, 2010 (0.2%), 2011 (0.1%) and 2012 (0.2%). The prevalence of HBsAg reported in year 2009 was 1.5%, 2010 (1.2%), 2011 (1.3%) and 2012 (1.4%). The prevalence of syphillis reported in year 2009 was 0.08, 2010 (0.01%), 2011 (0.09%) and 2012 (0.07%). The prevalence of malaria reported in year 2009 was 1%, 2010 (2.0%), 2011 (0.5%) and 2012 (0.5%). The prevalence of HCV reported in year 2009 was 0.6%, 2010 (0.9%), 2011 (0.7%) and 2012 (0.0%). Conclusion: The prevalence rate of TTIs reported from year 2009 to 2012 found to be decreased. This shows effective screening and availability of various tests for these pathogens.
Key words: Blood donor, syphilis, transfusion transmitted infections

Corresponding Author: Dr. Manisha Bhargava, Associate Professor, Department of General Pathology, Integral Institute of Medical Sciences and Research, Lucknow, U.P. India. This article may be cited as: Bhargava M, Chandra C. Transfusion transmitted infections among blood donors: A retrospective study. J Adv Med Dent Scie Res 2016;4(6):157-159.