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Volume 4 Issue 5 (September - October, 2016)

Original Articles

ASSESSMENT OF RETINAL FIBRE LAYER THICKNESS WITH THE HELP OF SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IN A GIVEN POPULATION-A CLINICAL STUDY
Niladri Saha

Background: Optical coherence tomography is one of the commonly employed imaging device which produces high resolution, cross-sectional images of retinal nerve fibre layer (RNFL) and optic nerve head. Spectral OCT is one of the commercially available spectral domain (SD) having an axial resolution of 5 μm. Great degree of variation exists while comparing the mean RNFL. Hence; we evaluated the retinal Nerve Fibre Layer Thickness using Spectral Domain OCT in North Bengal and adjacent area of Bihar, India. Materials & Methods: For this observational, cross-sectional study, 210 volunteers were recruited from the institute staff and patients with refractive error. All the subjects were classified into following groups depending on the visual activity. Subjects with best corrected visual activity of more than 23/30 and with refractive error within plus minus 3 dioptres (D) of sphere were categorized as having normal eyes. Subjects with plus minus 1.5 D of cylinder, intraocular pressure < 21 mmHg, clear ocular media on lens opacities classification system III, open angles on gonioscopy. The sectors were defined in clockwise order for right eye and counterclockwise order for the left eye. Only scans with signal strength of > 7 and no segmentation algorithm failures were included for analysis. In case of scan procedure, the strength of the signal was assessed and reviewed followed by exclusion of signal with strength of lesser than 15. Assessment of all the results was done using SPSS software.
Results: Non-significant results were obtained while comparing the mean value in males and females. The mean value of temporal quadrant in males and females was 70.5 and 70.9 respectively. The mean value of inferior quadrant was 142.2 and 143.8 respectively among males and females respectively. However, non-significant results were obtained while comparing the mean values of nasal quadrant and temporal sector among males and females. The mean value of nasal sector and superior nasal sector among males was 95.2 and 130.8 respectively while value of nasal and superior nasal sector among females was 96.7 and 128.5 respectively. Conclusion: For RNFLT, normative database is obtained in Indian eyes using SD-OCT. Future research in this field is recommended for better exploration of this area of medicine.
Key words: Optical coherence tomography, Retinal nerve fibre layer

Corresponding Author: Dr.  Niladri Saha, Associate Professor, Department of Ophthalmology, MGM Medical College and LSK Hospital, Kishanganj, Bihar

This article may be cited as: Saha N. Assessment of retinal fibre layer thickness with the help of spectral domain optical coherence tomography in a given population: A clinical study. J Adv Med Dent Scie Res 2016;4(5):114-117.

 
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