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Volume 6 Issue 6 (June, 2018)

Original Articles

Assessment of vitamin B- 12 level among pregnant women
Naveen Goyal, Sarika Gupta

Background: Pregnancy is a critical stage during the life cycle when the requirement for vitamin B12 increases due to the rapid cell multiplication resulting from the enlargement of the uterus, placental development and fetal growth. The present study assessed vitamin B- 12 level among pregnant women. Materials & Methods: 156 pregnant women of all trimester were enrolled and total vitamin B12 was measured using the IMMULITE 2500 analyzer. Results: 1st trimester had 45, 2nd had 50 and 3rd had 61 subjects. The difference was non- significant (P< 0.05). The mean Vit B- 12 (pmol/L) in 1st, 2nd and 3rd trimester was 320.4, 194.2 and 162.0 respectively and serum folate (nmol/L) level was 30.2, 18.6 and 15.2 in 1st, 2nd and 3rd trimester. The difference was significant (P< 0.05). Conclusion: Among all trimester, vitamin B- 12 level was lowered in pregnant women in third trimester, therefore oral supplement of vitamin B- 12 is necessary. Key words: Pregnancy, fetal growth, vitamin B- 12 level.

 
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