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Volume 9 Issue 3 (March, 2021)

Original Articles

Bone and joint manifestations in 25 hypothyroidism patients: A case series
Manish Garg, Deepika Aggarwal

Background: Hypothyroidism is frequently accompanied by musculoskeletal manifestations. Musculoskeletal symptoms associated with thyroid dysfunction include muscle weakness and pain, TM joint swelling and arthralgia, carpal tunnel syndrome and other neuropathic pains, and fibromyalgia-like complaints. Hence; in the present research, we aim to summarize the bone and joint manifestations in 25 hypothyroidism patients. Materials & methods: A Performa was made and complete medical history of all the patients was recorded. Blood samples were obtained and serum analysis was done. Radiographic investigations were carried out. On a separate Performa, bone and joint manifestations were recorded. All the results were summarized in Microsoft excel sheet and were analysed by SPSS software. Results: Mean age of the patients was 34.5 years. 60 percent of the patients were males while the remaining were females. Positive family history of thyroid dysfunction was seen in 16 percent of the patients. Epiphyseal dysgenesis, Slipped capital femoral epiphysis, Aseptic necrosis, Pseudogout/Gout, Erosive osteoarthritis, Epiphyseal dysgenesis and slipped capital femoral epiphysis were seen in 60 percent, 52 percent, 40 percent, 32 percent, 24 percent, 16 percent, 20 percent and 12 percent of the patients respectively. Conclusion: Thyroid hormones are essential for skeletal development and are important regulators of bone maintenance in adults. Hypothyroidism is frequently associated with bone and joint manifestation. Key words: Hypothyroidism, Bone, Joint

 
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