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Volume 8 Issue 3 (March, 2020)

Original Articles

A study of clinical and laboratory Profile of patients having Fever with Thrombocytopenia in a Tertiary Care Hospital
Dr. Shamim Ahmad Khan, Dr. Abdul Mateen Ansari

Background: Patients with acute febrile illnesses in a tropical country like India usually have an infectious aetiology and may have associated thrombocytopenia. Infections like malaria, dengue and typhoid are some of the common causes of fever with thrombocytopenia. Aim of the study: To clinical and laboratory profile of fever with thrombocytopenia in tertiary hospital. Materials and methods: The present study was conducted in the Department of General Medicine of the medical institution. For the study, a total of 50 patients admitted to the inpatient department with fever and thrombocytopenia were evaluated. History was taken regarding duration of fever, occupation and history of travel. Symptoms other than fever, headache, nausea, vomiting, abdominal pain, diarrhea, cough, anorexia, myalgia, gum bleeding, hemetemesis, oliguria, hematuria, loss of weight, etc., were noted. Signs like rashes, signs of dehydration, petechiae, jaundice, lymphadenopathy, hepatomegaly, splenomegaly, anemia, abdominal tenderness, altered sensorium, etc., were also noted. Follow up of all patients regarding treatment and outcomes were done during the hospital stay. Results: In the present study, 50 patients with fever and thrombocytopenia were evaluated. Number of male patients was 27 and female patients was 23. The mean age of patients was 38.75 years. It was observed that 17 patients had dengue which was the highest count. Malaria had second highest, which was 15. Septicemia, typhoid, viral hepatitis and alcoholic liver disease was diagnosed in 9, 5, 3 and 1 patient, respectively. All the mild thrombocytopenia patients recovered fully. There was one death in patients having moderate thrombocytopenia. A total of 3 deaths were seen in severe thrombocytopenia patients. Conclusion: Within the limitations of the present study, it can be concluded that dengue and malaria are the most common causes for fever with thrombocytopenia in our study population. The recovery rate of patients with mild and moderate thrombocytopenia is fairly positive. Keywords: fever, dengue, thrombocytopenia.

 
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