The craniofacial structures are mesenchymal cell derivatives. Mesenchymal stem cells are the progeny of mesenchymal cells following asymmetrical division and it reside in the various craniofacial structures in the adult. Cells with similar characteristics of adult stem cells have been isolated from the dental pulp, the deciduous dentition and the periodontium. Stem cell therapy has gained its attention from worldwide researchers. Craniofacial deformities like cleft lip and palate, ear microtia, craniofacial microsomia and head and neck cancers are not only major problem and it is considered as major burden in day today life. This article is an insight into the review of the current knowledge on stem cells and its extensive use in the orthodontics and dentofacial orthopaedics.
Keywords: stem cells, craniofacial anomaly, orthodontics.