Volume 8 Issue 9 (September, 2020)

Original Articles

Composition and structure of kidney stones in children with primary hyperparathyroidism
Abdusattor N. Nosirov, Fathulla F. Bayakhmedov, Izzatullo Z. Sobitov

Background: Urolithiasis in children is an important part of urological pediatric practice. Since it is recurring, every effort should be made to identify the underlying metabolic disorder causing her to ensure adequate treatment. In this article, we studied the chemical composition of urinary stones in children with kidney disease of primary hyperparathyroidism. Materials and Methods: The study was carried out using the method of X-ray diffraction analysis (X-ray diffraction), which was performed on a DRON-4 diffractometer (Russia). An analysis of the mineral composition of kidney stones was carried out in 54 children with nephrolithiasis (a comparison group) and 47 children with kidneys with primary hyperparathyroidism. Results: Unilateral kidney damage with calculus in patients with primary hyperparathyroidism occurred in 16 (15.1%) children, of which 4 (25%) children had multiple stones. Bilateral renal lesion with calculus was observed in 36 (69.2%) children, of which 12 (33.3%) had single-sided single stones, and 24 (67.6%) had multiple bilateral stones. In children with nephrolithiasis in primary hyperparathyroidism, 88 (kidneys) kidneys were affected by calculus. Among them, in 45 (51.1%) kidneys, coral stones were noted. Conclusion: A study showed that the mineral composition of kidney stones can be used to judge the damage to the skeletal system in primary hyperparathyroidism. They were characterized by phosphate stones, in the mineral composition of which apatites were found (81.1%) (hydroxylapatite, apatite, whitlockite, brushite, struvite-carbonate-apatite). Key words: kidneys, urinary stones, urolithiasis, hyperparathyroidism, parathyroid hormone.

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