|Saodat Yarmukhamedova, Feruz Nazarov, Xanuza Mahmudova, Nigora Vafoeva, Maxsuda Bekmuradova, Xudoyor Gaffarov, Doston Toirov, Murod Normatov, Suvon Yarmatov, Munira Xusainova
Hypertension is an urgent medical problem. As a result of the development of arterial hypertension, myocardial remodeling develops. Remodeling of the heart is a significant factor that, in turn, worsens the course and prognosis of the disease. The remodeling of the left ventricle in atheral hypertension has been studied quite well, but the state of the right ventricle has received much less attention. Right ventricular diastolic dysfunction is an independent predictor of survival. We studied the diastolic function of the right ventricle in 71 patients with various stages of hypertension and with concomitant heart failure of II-III functional classes. When analyzing the diastolic parameters of the right ventricle, depending on the level of elevation of diastolic blood pressure, significant differences were found between patients with mild and high arterial hypertension and related to the ratio of the maximum filling rate to the maximum expulsion rate with a tendency to increase the time of the rapid filling phase in diastole right ventricle, which is due to the initial signs of diastolic dysfunction of the right ventricle with a decrease in the maximum filling rate and a moderate increase in the contribution of right atrial systole to filling the right ventricle. A definite tendency towards a decrease in the ejection fraction of the right ventricle in patients with stage III hypertension was revealed; other clinical indicators between the subgroups practically did not differ. We have studied the parameters of the diastolic function of the right ventricle at different stages of hypertension, depending on the type of diastole disorders and low-symptom and severe heart failure. The addition of severe heart failure at various stages of hypertension leads to the appearance of more severe types of diastolic dysfunction of the right ventricle, which in some cases are restrictive. For patients with severe heart failure, a decrease in the contractility of the right ventricle is characteristic, which consists in a reliable, compared with control, a decrease in the maximum expulsion rate, a tendency to a decrease in the stroke volume and an increase in the end-diastolic volume of the right ventricle.
KEY WORDS: essential hypertension, right ventricle, diastolic function, heart failure, echocardiography.