Objective: To compare smear layer removal in the root canal dentin after final irrigation with 17% EDTA, QMix 2 in 1 and BioPure MTAD. Materials and Methods: Forty recently extracted mandibular premolars were taken and decoronated to a standardized root length of 12mm. They were prepared using ProTaper system up to size F3. Prepared teeth were randomly divided into 4 groups according to the final rinse solution: Group 1(distilled water, control), Group 2 (17% EDTA), Group 3 (QMix 2 in 1) and Group 4 (BioPure MTAD). Samples were split longitudinally into two halves and examined under scanning electron microscope for presence or absence of smear layer at coronal, middle and apical portions of root canal. Results: QMix 2 in 1 and BioPure MTAD were more effective in removing smear layer than 17% EDTA in the apical third of root canal. However, no significant difference was observed between EDTA, QMix and MTAD in removal of smear layer from coronal and middle third of the canal spaces. Conclusion: QMix 2 in 1 and BioPure MTAD are better final irrigating solutions than EDTA at the apical third of root canal dentin.
Key words: Root canal irrigation, EDTA, MTAD, QMix 2in1, smear layer, scanning electron microscopy.