Volume 8 Issue 6 (June, 2020)

Original Articles

Analysis of Prescription pattern and drug utilization in patients with acute coronary syndrome at a tertiary care teaching hospital in Jharkhand
Kunal Priyadarshi, A.K. Choudhury

Background: Acute coronary syndrome (ACS) refers to a group of conditions that include ST-elevation myocardial infarction (STEMI), non-ST elevation myocardial infarction (NSTEMI), and unstable angina. The present study was conducted to assess prescription pattern and drug utilization analysis in patients with acute coronary syndrome. Materials & Methods: The present study was conducted on 175 patients diagnosed with ACS of both genders. The drugs prescribed to the patients were evaluated whether the treatment given is in accordance with the guidelines provided by the ACC/AHA. Results: There were 110 males and 65 females in present study. The most commonly used anticoagulant was enoxaparin in 120 patients, commonly used antiplatelets was aspirin-clopidogrel combination in 135, thrombolytics was streptokinase in 26, statins was atorvastatin in 153, beta-blockers used was metoprolol in 104 and nebivolol in 65, nitrates was isosorbide mononitrate in 34, glyceryl trinitrate in 25 and ACEIs was ramipril in 145 patients. The difference was significant (p< 0.05). Over 90% of drugs were prescribed as per ACC/AHA guidelines except nitrates in which 52 patients received not as per ACC/AHA guidelines. The difference was significant (P< 0.05). The pattern of discharge medications prescribed to the patients was anticoagulants in 92%, antiplatelets in 95%, thrombolytics in 94.6%, statins in 99%, beta blockers in 97.5%, nitrates in 70% and ACEIs in 96%. Conclusion: Authors found that most of the drugs used for the management of ACS were as per According to the ACC/AHA guidelines. Key words: Acute coronary syndrome, antiplatelets, beta blockers.

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