Journal of AdvancedMedical and Dental Sciences Research

Background: Since numerous years antimicrobials are utilized to treat fungal and bacterial infections however their unfavourable impacts have lead researchers to think about their substitutes. Extremely minute examination is done on the antimycotic and antibacterial activity of certain plants is fairly specultative. In villages of Himachal Pradesh Zanthoxylum armatum leaves, fruits and stem are utilized to keep up oral hygiene by individuals and their oral hygiene was found comparable to those using other means to clean oral cavity. Aim of the present investigation was to check the antimicrobial activity of Z.armatum and to compare it with chlorhexidine and clotrimazole. Material and methods: The aqueous and ethanolic concentrates of dried fruits of Z.armatum were made and their antimicrobial impacts were analyzed. Results: Ethanolic extract was found to have progressive antimicrobial activity against tested bacterial and fungal aqueous extracts. Conclusion: Thus it can be concluded that Z.armatum has good antibacterial properties so it can be used as an active ingredient in plaque control measures. Key words: Antibacterial, Antifungal, Medicinal plants, Z.armatum