Background: Osteoarthritis (OA) is a common chronic condition resulting in pain, fatigue, functional limitations, increased healthcare utilization and high economic costs to society. The present study was undertaken for assessing the functional outcomes of Proximal Fibular Osteotomy in Osteoarthritis Knee. Materials & methods: A total of 20 patients with OA of knee were enrolled in the present study. The patients were placed in the supine position after administration of spinal anaesthesia. PFO was performed by removing a 2 to 3 cm length of fibula at a site 6 to 10 cm distal to the caput fibulae. Full weight bearing and free mobilization was allowed postoperatively. Knee ambulation activities was recorded using the knee function score. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Chi- square test was used for assessment of level of significance. Results: Mean time for full weight bearing was found to be 0.75 days. Mean duration of procedure was found to be 39.80 minutes. Postoperative wound infection was found to be present in 1 patient. Mean KSS functional score at preoperative, postoperative, postoperative 6 weeks, postoperative 12 weeks, postoperative 6 months and postoperative 9 months was found to be 45.85, 50.36, 55.86, 59.33, 65.37 and 68.19 respectively. Significant improvement in the mean KSS function score was seen at different postoperative time intervals. Conclusion: PFO is an innovative alternative method in the management of medial compartment arthritis of the knee and is associated with insignificant complications.