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Volume 7 Issue 9 (September, 2019)

Original Articles

A Hospital Based Study on effect of 2% Ketoconazole in Pityriasis Versicolor
Vineet Kumar, Rekha S, Jitendra Acharya

Introduction: Pityriasis versicolor is a frequent cutaneous fungal infection caused by lipophilic yeast Malasezia Furfur. The aim of our study was to assess the efficacy of ketoconazole 2% in a shampoo base in the treatment of pityriasis versicolor. Pityriasis versicolor (PV) is a widespread cutaneous fungal infection and caused by the lipophilic yeast Malassezia furfur . It is characterize by distinct scaly, discoloured or hypopigmented macules mainly on the upper trunk, proximal extremities and face. Material and methods: We enroll Fifty clinically diagnosed patients attend opd of department of skin &V.D.L. at s.n.medical college Jodhpur of pityriasis versicolor in the study. The signs and symptoms in the form of scaling, itching, erythema and hypo or hyperpigmentation were noted in each patient. Results: Fifty patients were enrolled in the study. Out of 36 males and 14 were females, Age ranged from 20 years to 40 years. Average duration of problem was 3 months (1 month – 6month). All the patients had hypopigmented macules and scaling; 13 patients complained of mild itching which worsened after sweating. Conclusion: The shampoo was applied daily for 15 days and found to be very efficient in clearing the Pityriasis Versicolor. There were no side effects. Ketoconazole 2% shampoo was shown to be highly effective and well tolerated for the treatment of PV, with significant reduction in scaling and elimination of the causative agent. Key words: Pityriasis versicolor, ketoconazole, Malassezia furfur.

 
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