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Volume 7 Issue 9 (September, 2019)

Original Articles

Comparison of intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients
Asiya Basheer

Background: Dexmedetomidine has activity at a variety of locations throughout the central nervous system. The present study was conducted to compare intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients. Materials & Methods: This present study was conducted on 40 pediatrics patients age ranged 4-10 years of age of both genders. Patients were divided into four groups on the basis of route and dose to be used for drug administration. In all groups, onset and depth of sedation, recovery time and drug acceptance was compared. Results: The mean onset on time in group I was 8.21 minutes, in group II was 7.47 minutes, in group III was 48.2 minutes and in group IV was 35.1 minutes. Depth of sedation was seen in 4 in group I, 9 in group II, 1 in group III and 0 in group IV. Recovery time was 97.2 minutes in group I, was 146.4 minutes in group II, was 89.2 minutes in group III and was 76.4 minutes in group IV. Drug acceptance was poor in 4 in group I, 3 in group II, 2 in group III, fair in 2 in group I, 1 in group II, 1 in group III, good in 4 in group I, 5 in group II, 2 in group II and 3 in group IV, excellent was 1 in group I, 6 in group III and 7 in group IV. The difference was significant (P< 0.05). Conclusion: Nasal administration of Dexmedetomidine is a safe and effective agent for procedural sedation in pediatric dental patients. Key words: Dexmedetomidine, Pediatric, Sedation

 
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