Journal of AdvancedMedical and Dental Sciences Research

Background: The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. The present study was conducted to assess  the utility and sensitivity of the cell block microscopy method and brush smears microscopy  in the cytodiagnosis of pleural effusions. Materials & Methods: The present study was conducted in the Department of General Pathology of Mulayam Singh Yadav Medical College, Meerut. It comprised of 100 specimens of brush tip washings from suspected cases of carcinoma lung. In all patients, comparison of brush smear microscopy and cell block microscopy was done. Results: Out of 100 patients, males were 60 and females were 40. Common findings was hilar mass seen in 40 patients, upper lobe mass in 24 patients, lower lobe mass in 10 patients, pleural effusion in 6 patients, cervical lymph nodes in 6 patients, x- ray opacity in 8 patients and multiple nodules in 6 patient. The difference was significant (P< 0.05). Conclusion: The CB method provides high cellularity, better architectural patterns, morphological features and an additional yield of malignant cells, and thereby, increases the sensitivity of the cytodiagnosis when compared with the CS method. Cell block preparation is a simple method that increases diagnostic yield of flexible bronchoscopy, is cost effective & hence can be routinely used.
Key words: Bronchoscopy, Cell block, Lung cancer, pleural effusions.

Received: 15 April, 2019                            Revised:  28 May 2019                             Accepted: 30 May 2019

Corresponding author: Dr. Pramila Gupta, Associate Professor,  Department of Pathology, Mulayam Singh Yadav Medical College, Meerut, U.P., India

This article may be cited as: Gupta P. Assessment of the utility and sensitivity of the cell block microscopy method and brush smears microscopy in the cytodiagnosis of pleural effusions. J Adv Med Dent Scie Res 2019;7(6): 114-116.