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Volume 7 Issue 6 (June, 2019)

Original Articles

A case control study to evaluate the prevalence of thyroid dysfunction in Type 2 Diabetes Mellitus
Hari Kant Tiwari, Pankaj Kumar

Aim: Present study was done to evaluate the prevalence of thyroid dysfunction in Type 2 Diabetes Mellitus and the spectrum of thyroid dysfunction. Material and methods: This case control study was conducted in Family Medicine outpatient clinics in Lucknow. A total of 100 cases diagnosed with Type-2 Diabetes Mellitus and 100 healthy controls were taken randomly. Thyroid function tests were conducted using the chemiluminescence assay. Statistical Analysis: The data was tabulated and Statistical analysis was performed using the Chi-square test for categorical variables. Student’s t-test was used for finding significance between the means.  P value ≤ 0.05” was considered statistically significant. Results: 26 patients had thyroid dysfunction which was found to be significantly more in type 2 DM than in healthy controls. Among those diabetic patients with thyroid dysfunction, 17 were females. The mean body mass index was high in diabetic patients with thyroid dysfunction. The hemoglobin A1c levels in patients who had thyroid dysfunction were high. Those with thyroid dysfunction had a mean total cholesterol level higher than euthyroid diabetics and controls. Goiter was found to be present in 3 of cases of Type 2 DM. Conclusion: Type 2 DM and thyroid diseases have a significant association. Subclinical hypothyroidism and overt hypothyroidism were the most common thyroid abnormality in Type 2 DM. Thyroid dysfunction was associated with worsening dyslipidemia in Type 2 DM.

Key words: Subclinical Hypothyroidism, Thyroid Dysfunction, Type 2 Diabetes Mellitus

Received: 11 April, 2019                            Revised:  27 May 2019                             Accepted: 30 May 2019

Corresponding author: Dr. Pankaj Kumar, Associate Professor, Department of Medicine, TS Misra Medical College & Hospital Lucknow, Uttar Pradesh, India

This article may be cited as: Tiwari HK, Kumar P. A case control study to evaluate the prevalence of thyroid dysfunction in Type‑2 Diabetes Mellitus. J Adv Med Dent Scie Res 2019;7(6): 57-59.

 
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