Journal of AdvancedMedical and Dental Sciences Research

Background: Many oral squamous cell carcinomas develop from potentially malignant disorders (PMDs). Correct diagnosis and timely treatment of PMDs may help prevent malignant transformation in oral lesions. Hence; under the light of above mentioned data, we planned the present study to estimate serum lipid profile in patients with premalignant disorders. Materials & method: A total of 25 patients with presence of any form of premalignant pathology, as diagnosed and confirmed with histopathologic examination, were included in the present study. Another 25 age- and gender matched healthy controls who reported for routine medical checkup were also included. Complete demographic details of all the subjects were obtained. Blood samples were obtained from all the subjects and were sent to central laboratory where an auto analyzer was used for evaluation of serum lipid profile. Results: Significant results were obtained while comparing the mean serum lipid profile in between the premalignant group and the control group in the present study. Conclusion: Alteration in serum lipid profile in patients with premalignant disorders might have both diagnostic and prognostic implication.
Key words: Lipid, Oral cancer, Premalignant.                 

Received: 11 May, 2019                            Revised:  28 May 2019                             Accepted: 29 May 2019

Corresponding author: Dr. Namita Sepolia, MDS, Private consultant, J & K, India.

This article may be cited as: Sepolia N, Mahajan S. Estimation of serum lipid profile in patients with premalignant disorders. J Adv Med Dent Scie Res 2019;7(6): 35-37.