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Volume 4 Issue 5 (September - October, 2016)

Original Articles

Assessment of Mean Platelet Volume in Diabetics and Non-Diabetics- A Clinical Study
Siddharth Sonkar

Background: Diabetes mellitus (DM) is a widespread disease, currently the most common endocrine disorder around the world. The present study was conducted to determine mean platelet volume in diabetics and non-diabetics. Materials & Methods: The present study was conducted in the department of general medicine. It comprised of 80 patients with diabetes mellitus of both genders. 40 subjects were selected as control. Patients were divided into 3 groups of 40 each. Group II were type II diabetics without retinopathy, group II were type II diabetics with retinopathy and group III were non diabetics (control). Mean Platelet volume (MPV) estimation was done in the laboratory by five part fully automatic hematology analyzer by Horiba ABX pentra 80. Results: In group II, maximum subjects (12) were in age group 41-50 years, in group II in age group 41-50 years (14). Similarly, in group III, maximum subjects were in 41-50 years age group (13). The difference was non- significant (P> 0.05). The mean platelet volume in group I was 8.58± 0.32 fL, in group II was 9.86± 0.38 fL and in group III was 7.62± 0.25 fL. The difference was significant (P< 0.05). Conclusion: Mean platelet volume might be used as a simple and cost-effective laboratory test in the follow up of diabetes mellitus along with HbA1c. There is a close relationship between poor glycemic control and increased platelet activity in patients with type 2 DM.
Key words: Diabetes mellitus, platelet volume, Retinopathy

Corresponding Author: Dr. Siddharth Sonkar, Assistant Professor, Department of Medicine, Prasad Institute of Medical Sciences Lucknow, Uttar Pradesh, India

This article may be cited as: Sonkar S. Assessment of Mean Platelet Volume in Diabetics and Non-Diabetics- A Clinical Study. J Adv Med Dent Scie Res 2016;4(5):156-158.

 
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