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Volume 7 Issue 2 (February, 2019)

Original Articles

Association of hs-CRP in Centrally Obese Patients with and without Metabolic Syndrome- A Clinical Study
Bhupinder Singh, Ashwani Kumar Sharma, Harsh Bala Gupta, Hardip Singh, Simranjit Kaur

Background: Overweight and obesity are defined as abnormal or excessive fat accumulation that presents a risk to health. The present study has been designed to determine the correlation of hs-CRP in centrally obese patients with and without metabolic syndrome. Materials & Methods: The present study comprised of one hundred (100) obese patients, over 20 years of age. In all subjects, blood pressure and body weight was measured. Body Mass Index (BMI) and Waist circumference (WC) were measured. hs- CRP was performed with ‘Dr. Turbichem hs-CRP diagnostic kit. Results: All the patients (100%) had central obesity. Out of the total, fifty 50 (50%) were fulfilling the criteria for metabolic syndrome. Fifty patients with metabolic syndrome comprised of 33 males (66%) and 17 females (34%), with male to female ratio as 1.94: 1. Most of the patients i.e. 29 (58%) were between 41 to 60 years of age. A significant difference in mean hs CRP value in subjects with different waist circumference, triglycerides (mg/dl), HDL cholesterol, blood pressure (mmHg), fasting glucose (mg/dl), number of criteria and presence or absence of metabolic syndrome. Conclusion: High sensitivity CRP can be used as surrogate marker of chronic inflammation in metabolic syndrome. There was a significant increasing trend in mean levels of hs-CRP as the components of metabolic syndrome increased, suggesting the fact that higher the number of components of metabolic syndrome in a patient, higher the risk of cardiovascular events.
Key words: Metabolic syndrome, Obesity, Triglyceridemia.

Received: 15 December   2018                                 Revised: 26 December 2018                          Accepted: 27 December 2018
Corresponding author: Dr. Hardip Singh, Associate Professor, Department of Medicine, G.M.C. Amritsar, Punjab, India
This article may be cited as: Singh B, Sharma AK, Gupta HB, Singh H, Kaur S. Association of hs-CRP in Centrally Obese Patients with and without Metabolic Syndrome- A Clinical Study. J Adv Med Dent Scie Res 2018;7(2):13-17.

 
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