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Volume 6 Issue 6 (June, 2018)

Review Articles

Role of Angiogenesis in Oral Squamous Cell Carcinoma – A Review
K.Indra priyadharshini, R.Saranyan, R.Madhavan Nirmal, B.Sekar

Angiogenesis, the process that leads to the formation of new blood vessels, it is main hall mark of carcinogenesis in tumour progression. It plays major has been studied in many type of human cancer including head and neck cancer. Squamous cell carcinoma of head and neck is the sixth most common cancer in worldwide. In the last year many efforts have been made to understand mechanisms necessary to the formation of new blood vessels in tumour tissue. Main goal of this review to understand the tumour angiogenesis and it is angiogenic markers will facilitate accurate identification of tumour transformation, progression and metastasis. Targeting tumour angiogenesis with specific inhibitors that will help in treatment of oral squamous cell carcinoma. Key words: Angiogenesis , angiogenic marker, tumour progression , metastasis , angiogenic inhibitors , angiogenic promoters

 
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