Journal of AdvancedMedical and Dental Sciences Research

Background: Lichen planus (LP) is a chronic mucocutaneous disorder that affects oral and genital mucous membranes, skin, nails, and scalp. The present study was conducted to compare 0.1%, triamcinolone acetonide and 0.1% tacrolimus in the management of oral lichen planus. Materials & Methods: The present study comprised of 50 patients of oral lichen planus which was confirmed by clinical examination followed by histopathological examination. They were divided into 2 groups of 25 each. Group I were those who were prescribed 0.1% tacrolimus 4 times daily and group II were put on 0.1% triamcinolone acetonide 4 times daily. Patients were recalled regularly to see improvement in the lesion and were recorded as improved and non- improved. Results: Pain was present in 12 patients in group I and 14 in group II and burning sensation was present in 17 in group I and 19 in group II patients. The difference was non- significant (P> 0.05). Improvement was seen in 18 in group I and 19 in group II and non improvement in 7 in group I and 6 in group II. The difference was non- significant (P> 0.05). Conclusion: OLP is an inflammatory mucosal and cutaneous disorder commonly seen among females. Both 0.1%, triamcinolone acetonide and 0.1% tacrolimus found to be effective in the management of oral lichen planus. Key words: inflammatory, OLP, mucosal.