Journal of AdvancedMedical and Dental Sciences Research

Department of Oral Pathology, 1Chettinad Dental College and Hospital, Chennai, 2Sri Sai Dental College and Hospital, Vikarabad, 3Adiparashakthi Dental College, Melmarvathur, Tamil Nadu.

A rare, recalcitrant, and lethal form of leukoplakia necessitate special attention. The purpose of this review is to further educate and to characterize the risk factors, clinical course, and optimal treatment for this highly aggressive, premalignant oral lesion. White lesions are relatively frequent in the oral cavity with prevalence of approximately 24.8%. Among them oral leukoplakia (OL) is quite prevalent (0.2-3.6%). Hansen et al in a retrospective study reported that 26 of the 30 lesions initially diagnosed as OL became oral carcinomas in patients followed for 1-20 years (average, 6.1 years). After this study, these lesions were named oral proliferative verrucous leukoplakia (OPVL).  World Health Organization nomenclature, OPVL conforms to the new terminology of “potentially malignant disorders” given that it is neither a delimited lesion nor a condition.
Key words: Oral proliferative verrucous Leukoplakia (OPVL), White Lesion, Leukoplakia

Corresponding Author: Dr Aesha, Senior lecturer, Department of oral pathology, Chettinad dental college and hospital, Kanchepuram, Tamil Nadu.
This article may be cited as: Aesha S, Tanveer S, C Sreeja, Kumar SM, Devi..  Proliferative Verrucous Leukoplakia – A Recalcitrant. J Adv Med Dent Scie Res 2014;2(4):75-79.