Journal of AdvancedMedical and Dental Sciences Research

Background: Cirrhosis is an advanced stage of liver fibrosis that is accompanied by distortion of the hepatic vasculature. Physicians involved in the care of patients with cirrhosis recognize that the development of renal dysfunction is associated with significant morbidity and mortality.Hence; we planned the present study to assess to correlation of renal manifestation with severity of disease in liver cirrhosis patients. Materials & methods: We planned the present study to assess correlation of renal manifestation with severity of disease in liver cirrhosis patients. A total of 30 patients with cirrhosis of liver were included in the present study. Complete clinical examination of all the patients was done. Detailed history of all the patients was obtained. Hematological tests like hemoglobin, white blood cell count, differential count, platelet count, prothrombin time, and erythrocyte sedimentation rate, along with complete renal and hepatic profile in all the patients was done. Child pugh score grading system was used for grading the severity of liver cirrhosis. All the results were compiled and analyzed by SPSS software.  Results: Alcohol was the most common etiologic factor seen to be present in 60 percent of the patients of the present study. 19 patients out of the total 30 patients were graded as ‘C’ according to the child pugh score grading system. Conclusion: Renal profile is significantly associated with severity of diseases in liver cirrhosis patients.
Key words: Liver cirrhosis, renal profile

Corresponding Author: Dr. Sorabh Gupta, Associate Professor, Department of Medicine, Mayo Institute of Medical Sciences Barabanki, U.P., India

This article may be cited as: Kumar P, Gupta S. Renal Profile in Liver Cirrhosis Patients: An Observational Study. J Adv Med Dent Scie Res 2016;4(3):141-143.