Journal of AdvancedMedical and Dental Sciences Research

ABSTRACT: Background: Lipid profile is better predictor of cardiovascular diseases. This study was conducted to determine the lipid profile and central arterial stiffness in study population. Materials & Methods: This study was conducted in the department of Physiology on 120 healthy subjects. In all pulse wave velocity and intima media thickness was done. Results: Males were 55 and females were 65. The difference was non- significant (P> 0.05). Maximum number of subjects had s. cholesterol <150 (56) followed by 150-250 (38) and >250 (26). Males have higher Av C-F PWV and Av CIMT as compared to females. The difference was significant (P< 0.05). C-F PWV and CIMT determination based on LDL also revealed that both values were significantly higher in males as compared to females (P< 0.05). Distribution of C-F PWV and CIMT according to HDL showed decrease in both values as HDL level increases. Level was more in males than females and difference was significant (P< 0.05). Conclusion: Increased level of LDL, VLDL and decrease level of HDL indicates increase in arterial stiffness and carotid intima media thickness. Key words: Intima, Lipid, Pulse .