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Volume 5 Issue 8 (August, 2017)

Original Articles

Effect Of Local Periodontal Treatment Alone And In Combination With Systemic Doxycycline Therapy On Glycaemic Control In Patients With Type-2 Diabetes Mellitus
Madhavi Singh, Manish Goutam

Background: Evidence consistently shows that Periodontal infection may adversely affect glycaemic control in people with diabetes.  In the light of this background this study aims to examine the effects of non-surgical periodontal treatment alone and incorporating systemic doxycycline on glycaemic control in patients with type 2 diabetes mellitus (type 2 DM) who have generalized periodontitis. Aim: The aim of the study was to assess the effect of local periodontal treatment alone and in combination with systemic doxycycline therapy on glycaemic control in patients with type-2 diabetes mellitus. Materials And Methods: A total of 30 type 2 DM patients with generalized periodontitis were selected for the study. The selected patients were randomly assigned to three groups (groups A, B, and C) comprising 10 patients each, GroupA and Group B where the (TG) Treatment groups : Group A received treatment with scaling and root planing only. Group B received treatment with scaling and root planing followed by systemic doxycycline. Group C received no treatment (control group). The clinical parameters were recorded like plaque index, gingival index, probing pocket depth, and clinical attachment level, at baseline (day zero),  and at the end of 3 months. The Lab investigation for glycated hemoglobin (HbA1c) was recorded at baseline (day zero) and at the end of 3 months. Results: Both therapies resulted in a statistically significant improvement for periodontal parameters for both group A and group B (treatment groups) as  compared to the control group, whereas, patients in Group B treated with SRP + systemic doxycycline  showed  enhanced gains in CAL (p <0.001) over a period of 3 months as compared to Group C.  HbA1c values showed a statistically significant decrease in treatment groups for both the therapies equally as compared to the control group. Conclusions: with this study its concluded that nonsurgical periodontal therapy shows a definite  improvement of  glycemic control in patients with T2DM, but no statistical difference was observed with adjunctive systemic doxycycline therapy. A further study with a larger sample size is required.
Key words: Glycated hemoglobin,  chronic periodontitis, type 2 diabetes mellitus, doxycycline

Corresponding author: Dr. Madhavi Singh, Department of Periodontics, Peoples Dental Academy,Bhopal. Email: drmadhvisinghperio@gmail.com

This article may be cited as: Singh M, Goutam M. Effect Of Local Periodontal Treatment Alone And In Combination With Systemic Doxycycline Therapy On Glycaemic Control In Patients With Type-2 Diabetes Mellitus. J Adv Med Dent Scie Res 2017;5(8):74-82.

 
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