Oral leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence increases with age, ranging from less than 1% in men under age 30 years to 8 % in men and women over age 70 years. There may be several routes to malignant transformation of oral leukoplakia, including transformations induced by carcinogenesis due to betel quid chewing or smoking, or by HPV infection. The only significant factors associated with it are clinical type and size of lesion. Although epithelial dysplasia is an important predictive factor of malignant transformation, it should be realized that not all dysplastic lesions will become malignant. This systemic review presents a retrograde analysis of malignant transformation of leukoplakia in the Asian scenario. The review was undertaken to address the objective of demographic and clinicopathologic factors involved in malignant transformation of oral leukoplakia.
Key words: Oral leukoplakia, Malignant transformation, Epithelial dysplasia.
Corresponding author: Preetinder Kaur, BDS (Intern), Sri Guru Ram Das Institute of Dental sciences & Research, Amritsar, Punjab, India
This article may be cited as: Kaur P, Singh T, Kour S. Malignant Transformation Of Oral Leukoplakia: An Asian Scenario. J Adv Med Dent Scie Res 2017;5(8):70-73.