Journal of AdvancedMedical and Dental Sciences Research

Human papillomavirus (HPV) contamination is the most usually analyzed sexually transmitted disease. HPV contamination has been etiologically connected with condyloma acuminatum, squamous intraepithelial lesions, and anogenital malignancy, including cervical, vaginal, vulval, penile, and anal carcinoma. Numerous patients with oropharyngeal squamous cell carcinomas, especially those emerging in the base of the tongue and in the tonsillar district, don't have the conventional hazard factors related with head and neck malignancies (eg, smoking, smokeless tobacco, liquor utilization). Epidemiologic and atomic examinations have recognized the HPV-16 genotype of HPV as a causative specialist in a hefty portion of these patients. Other high-hazard HPV genotypes, for example, HPV-18, 31, or 33, are likewise causative yet are less normal. These high-hazard HPV contaminations may likewise seldom cause tumors at other head and neck sites.2 The part of HPV disease in head and neck squamous cell carcinoma is discussed here.
Key words: HPV, Cancer, Oral squamous cell carcinoma.