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Volume 4 Issue 6 (November - December, 2016)

Original Articles

HISTOPATHOLOGICAL STUDY OF LESIONS OF NASAL CAVITY- A CROSS SECTIONAL STUDY
Pragat Gupta, Sweta Anand

Background: A variety of non-neoplastic and neoplastic lesions in the nasal cavity, paranasal sinuses and nasopharynx are commonly seen in today’s life. Polypoidal mass in the nose is a very commonly seen lesion and it can be an inflammatory polyp, granuloma, tumour, either benign or malignant. The present study was conducted to study the histopathogy and classify the lesions of nasal cavity. Materials & Methods: This study was conducted in the department of General Pathology in year 2012. It included 90 patients with polypoidal lesions of nasal cavity. All the specimens were fixed in 10% formalin, processed and embedded in paraffin. Sections of 3-4 μm thick were cut, and stained with Haematoxylin and Eosin (H & E). Histologically the polyps were classified into simple (non neoplastic) polyps and neoplastic. Results: Out of 90 patients, 50 were males and 40 were females. The difference was non – significant (P- 0.2). Age group 0-10 years had 2 males and 4 females. Age group 10-20 years had 12 males and 9 females. Age group 21-30 years had 10 males and 11 females. Age group 31-40 years had 8 males and 7 females. Age group 41-50 years had 9 males and 4 females. Age group 51-60 years had 5 males and 3 females. Patients with >60 years had 4 males and 2 females. The difference was non – significant (P > 0.05). 72 (80%) had non neoplastic lesions and 18 (20%) had neoplastic lesions. Among non neoplastic lesion, 44 were seen in males and 28 in females. In neoplastic lesion, 6 were seen in males and 12 in females. The difference was significant (P < 0.05). Among non neoplastic lesions, 30 (42%) were allergic and 42 (58%) were non allergic. Among non allegic lesions, 18 were non specific, 8 were of rhinosporidiosis, 10 were of rhinoscleroma and 6 were of mucormycosis. The difference was non significant (P > 0.05). 14 were benign lesions and 4 were malignant lesions (SCC). The difference was significant (P < 0.05). Among benign lesions, 4 were of inverted papilloma, 5 were of neurilemmoma and 3 were of angiofibroma. The difference was non - significant (P > 0.05). Conclusion: Nasal lesions are common with predominance in 2nd and 3rd decades. Most of them are non neoplastic which further of allergic and non allergic type. Male predilection is seen.
Key words: Benign, malignant, mucormycosis

 
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