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Volume 3 Issue 6 December (Supplement2) 2015

Original Articles

STUDY OF SERUM LIPID PROFILE IN PREGNANCIES COMPLICATED BY PREECLAMPSIA
Mahadev Patel, Nishant Pujara

Objective: To evaluate the lipid profile among patients who present preeclampsia and correlate these parameters with 24-hour proteinuria. Methods::This study involved 42 women with preeclampsia and 35 healthy pregnant women in the third trimester of pregnancy as controls. Blood samples were obtained from all the patients, and the serum levels of triglycerides, total cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL) and very low density lipoproteins (VLDL) were determined. Cases and controls were matched for maternal age, gestational week and body mass index. Results: The VLDL and triglyceride values from the women with preeclampsia were significantly higher than those of the healthy women. There was a positive correlation between increased proteinuria and higher VLDL and triglyceride levels in patients with preeclampsia. Conclusion: Among the patients with preeclampsia, higher VLDL and triglyceride levels were positively correlated with proteinuria. These observations indicate that the pregnant women who presented elevated lipid levels were more susceptible to cardiovascular disorders and, consequently, pre-eclampsia. 
Key words: Cholesterol, lipid profile, preeclampsia, pregnant

 
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