Journal of AdvancedMedical and Dental Sciences Research

Background: Local anesthetic drugs, by disrupting nerve conduction lead to a temporary numb into the specific area of the body. The present study compared effect of mepivacaine and lignocaine on heart rate in children. Materials & Methods: 60 children age <14 years of both genders were divided into 2 groups of 30 each. Group I received 2% lidocaine with adrenaline 1: 80000 and group II received 3% Mepivacaine. In both groups heart rate was recorded before and after injection and compared. Results: Group I received 2% lidocaine with adrenaline 1: 80000 and group II received 3% Mepivacaine. Group I comprised of 20 males and 10 females and group II had 18 males and 12 females. Heart rate was 74.2 beats/ min before and 83.5 beats/ min after injection. In group II, heart rate was 82.5 beats/ min before and 83.7 beats/ min after injection. The difference was significant (P< 0.05). Conclusion: Mepivacaine did not alter heart rate whereas with lignocaine having added adrenaline there was more change in heart rate after injection. Key words: Heart rate, Lignocaine, Mepivacaine