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Volume 9 Issue 2 (February, 2021)

Original Articles

A comparison of different drugs in treatment of Dermatophytic infections
Anil Goyal

Background: Dermatophytic infections are the most common fungal infections affecting 20%–25% population globally. The present study compared different treatment modalities in dermatophytic infections. Materials & Methods: 70 patients with dermatophytoses were randomly divided into 2 groups of 35 each. Group I patients were prescribed tab. terbinafine 500 mg daily for 4 weeks and group II received tab. itraconazole 200 mg for 4 weeks daily. Clinical response was noted including pruritus, erythema and scaling. Results: Group I had 15 males and 20 females and group II had 18 males and 17 females. Scaling score was 1.86, 1.08 and 0.49 in group I and 1.66, 1.08 and 0.16 in group II at baseline, 2 weeks and 4 weeks respectively. Erythema score found to be 1.54, 1.04 and 0.36 in group I and 1.20, 0.95 and 0.11 in group II, pruritis score was 2.32, 1.42 and 0.74 in group I and 2.14, 1.04 and 0.22 in group II at baseline, 2 weeks and 4 weeks respectively. The difference was significant (P< 0.05). Conclusion: Authors found that dermatophytes is common infection among both genders. Both itraconazole and terbinafine were effective and safe. Key words: Dermatophytes, Itraconazole, terbinafine.

 
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