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Volume 8 Issue 12 (December, 2020)

Original Articles

Evaluation of CRP levels in patients with periodontitis- A cross-sectional study
Dr. Shipra Sepolia, Dr. Soujanya Koyalada

Background: CRP levels have a significant role as a biomarker for confirmation of role of inflammation in chronic periodontitis which may pose as a risk factor for other systemic diseases. Aim: The aim of the study was to evaluate serum C-reactive protein levels in chronic periodontitis. Materials and methods: This prospective cross-sectional study was comprised of 200 subjects suffering from various grades of periodontitis and normal controls (n=100). Oral prophylaxis and root scaling was performed 3 months prior to blood collection. Samples were collected at three spaced visits and clinical parameters of plaque index, gingival index, clinical loss of attachment and pocket depths were recorded. Statistical analysis was performed by using the Analysis of Variance (ANOVA) tool. Results: A significant reduction in serum CRP levels was seen concomitantly with improvement in clinical parameters- CAL and pocket depths. Conclusion: It can be concluded from the study that serum CRP levels may act as a biomarker of improvement in periodontal health. Keywords: Serum, CRP, periodontitis, Pocket depth, Clinical loss of attachment.

 
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