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Volume 8 Issue 12 (December, 2020)

Original Articles

Clinico-pathological spectrum of lichen planus in 82 cases
Dr. Ishani Gupta, Dr. Reeta Sood, Dr. Subhash Bhardwaj

Background: The present study was conducted to assess histopathology of lichen planus. Materials & Methods: 82 patients of lichen planus was recorded. Biopsy of skin lesions was done and sent for histopathological examination. Specimens were studied with H & E stains. Results: Common type was classical in 35, hypertrophic in 22, linear in 11, follicular in 8, annular in 5 and LP Pigmentosus in 1 patient. The difference was significant (P< 0.05). Common histological findings were hyperkeratosis in 80, basal cell degeneration in 82, focal hypergranulosis in 76, band like inflammatory infiltrate in 56, pigment incontinence in 82, saw-tooth rete ridges in 42 and colloid bodies in 30 patients. The difference was non- significant (P> 0.05). Conclusion: Clinico pathological correlation is the key to confirm the diagnosis for further patient care and treatment. Most common clinical form found was classical type. The most consistent histopathological findings were basement membrane degeneration, band like lymphocytic infiltrates and melanin incontinence. Key words: hyperkeratosis, histopathological, Lichen Planus

 
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